Gas Chromatography of Urinary Anthranilic Acid and 3-Hydroxyanthranilic Acid by Solvent Extraction Method
نویسندگان
چکیده
منابع مشابه
On the Biological Importance of the 3-hydroxyanthranilic Acid: Anthranilic Acid Ratio
Of the major components of the kynurenine pathway for the oxidative metabolism of tryptophan, most attention has focussed on the N-methyl-D-aspartate (NMDA) receptor agonist quinolinic acid, and the glutamate receptor blocker kynurenic acid. However, there is increasing evidence that the redox-active compound 3-hydroxyanthranilic acid may also have potent actions on cell function in the nervous...
متن کامل3-hydroxyanthranilic Acid Metabolism
The participation of 3-hydroxyanthranilic acid as an intermediate in the biosynthesis of nicotinic acid from tryptophan was first demonstrated in certain mutant strains of Neurospora in 1948 by Bonner (1) and by Mitchell and Nyc (2). In addition, Mitchell et al. (3) found that 3-hydroxyanthranilic acid can replace nicotinic acid in the nutrition of the rat. In 1946 Singal et al. (4) noted a sub...
متن کاملDEVELOPMENT OF A METHOD FOR THE DETERMINATION OF 4-HYDROXY-3-METHOXYMANDELIC ACID (VANILLYLMANDELIC ACID) IN URINE BY PAPER CHROMATOGRAPHY
We have developed a simple and precise paper chromatographic method for the determination of 4-hydroxy-3-methoxymandelic acid (VMA) in urine. Concentrations of VMA in patients with neuroblastoma were increased in comparison to controls. The linearity was excellent in the concentration range tested. The within-assay coefficient of variation for control and patient urine was less than 2.2%. ...
متن کاملEnzymatic conversion of 3-hydroxyanthranilic acid to nicotinic acid.
The apparent conversion of tryptophan to nicotinic acid has been observed for several animal species (cf. (1)). Other studies demonstrated that at least some of the nicotinic acid (or amide) was synthesized within the tissues of the animal (2, 3). It was of interest to extend these studies and the ability of liver slices to synthesize nicotinic acid from its biologically active intermediate, 3-...
متن کاملSolvent Extraction and Spectrophotometric Determination of Magnesium by Paratoly l-2-Thenohydroxamic Acid and Quinalizarin
Magnesium is extracted with a chloroform solution of N-p-tolyl-2- thenohydroxamic acid (PTTHA) from aqueous solution of pH 9.5 .Mg-PTTHA complex is colourless and the colour is developed by adding quinalizarin into the extract. lmax and e of the complex are 590nm and 2.8´103 Lmol -1cm-1respectively.Most common ions do not interfere in the determination of magnesi...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1972
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.20.1412